Mepixanox

Mepixanox
Clinical data
ATC code	R07AB09 (WHO) ;
Identifiers
	IUPAC name 3-Methoxy-4-(piperidin-1-ylmethyl)-9H-xanthen-9-one;
CAS Number	17854-59-0 ;
PubChem CID	65687;
ChemSpider	59116 ;
UNII	7419T4YQQW;
KEGG	D07410 ;
ChEMBL	ChEMBL2104462 ;
CompTox Dashboard (EPA)	DTXSID90170504 ;
ECHA InfoCard	100.037.994
Chemical and physical data
Formula	C20H21NO3
Molar mass	323.392 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3O2)CN4CCCCC4;
	InChI InChI=1S/C20H21NO3/c1-23-17-10-9-15-19(22)14-7-3-4-8-18(14)24-20(15)16(17)13-21-11-5-2-6-12-21/h3-4,7-10H,2,5-6,11-13H2,1H3 ; Key:PYSOHOOUXFWCFF-UHFFFAOYSA-N ;
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Mepixanox (Pimexone) is a respiratory stimulant (analeptic).^[1] According to the primary source, it is stated to be a central nervous system stimulant, which is an endemic/inherent property of many of the analeptic drugs.^[2]

References

↑ Allen RC (1985). Chapter 32. To Market, to Market—1984. Annual Reports in Medicinal Chemistry. Vol. 20. pp. 315–325. doi:10.1016/S0065-7743(08)61058-1. ISBN 9780120405206.
↑ Da Re, P., Sagramora, L., Mancini, V., Valenti, P., Cima, L. (May 1970). "Central nervous system stimulants of the xanthone series". Journal of Medicinal Chemistry. 13 (3): 527–531. doi:10.1021/jm00297a042. PMID 5441136. Retrieved 1 September 2026.

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[1] Allen RC (1985). Chapter 32. To Market, to Market—1984. Annual Reports in Medicinal Chemistry. Vol. 20. pp. 315–325. doi:10.1016/S0065-7743(08)61058-1. ISBN 9780120405206.

[2] Da Re, P., Sagramora, L., Mancini, V., Valenti, P., Cima, L. (May 1970). "Central nervous system stimulants of the xanthone series". Journal of Medicinal Chemistry. 13 (3): 527–531. doi:10.1021/jm00297a042. PMID 5441136. Retrieved 1 September 2026.

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v t e Other respiratory system products (R07)
Lung surfactants	Colfosceril palmitate Dipalmitoylphosphatidylcholine
Respiratory stimulants	Almitrine Amiphenazole Bemegride Dimefline Doxapram Etamivan GAL-021 Mepixanox Nikethamide Pentetrazol Prethcamide
5-HT4 receptor agonists	BIMU-8 Zacopride
Other agents for treating respiratory depression	Ivacaftor (+ lumacaftor, + tezacaftor, + elexacaftor/tezacaftor) Nitric oxide Vanzacaftor/tezacaftor/deutivacaftor BW373U86 CX-546 CX-717