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Dimethyldisulfanilamide

From Wikipedia, the free encyclopedia

4'-(Dimethylsulfamoyl)sulfanilanilide
Clinical data
Other namesDiseptal A; Albasil; Uleron; Uliron
Identifiers
  • 4-Amino-N-[4-(dimethylsulfamoyl)phenyl]benzenesulfonamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H17N3O4S2
Molar mass355.43 g·mol−1
3D model (JSmol)
  • CN(C)S(=O)(=O)C1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N
  • InChI=1S/C14H17N3O4S2/c1-17(2)23(20,21)14-9-5-12(6-10-14)16-22(18,19)13-7-3-11(15)4-8-13/h3-10,16H,15H2,1-2H3
  • Key:TYDVXCIBGRTKRO-UHFFFAOYSA-N

Dimethyldisulfanilamide (also known by the brand name Uliron) is a historical sulfonamide antibiotic introduced in 1938 by IG Farben, commonly used during the late 1930s and early 1940s to treat gonorrhea, particularly when earlier sulfonamides like Prontosil were ineffective.[1] It was highly regarded during that period for its rapid action in treating gonorrhea and soft chancre (ulcus molle).[2]

References

[edit]
  1. ↑ O'Malley K (April 1938). "A new chemotherapeutic agent in gonorrhoea: preliminary report". South African Medical Journal. 12 (8): 301–303.
  2. ↑ Pfister OM (January 1938). "A New Antigonorrhoeal Drug, Uliron". Chinese Medical Journal. 54 (5): 416–420.