Baljet reaction
The Baljet reaction is a qualitative and quantitative method of analysis published by Henri Baljet[1] in 1918.[2] This chemical reaction is used for the detection and colorimetric[3] determination of cardenolides. To the sample, an aqueous hydroxide solution and an ethanolic picric acid solution are combined and added, with a positive test turning orange or red.[4][5] The mechanism involves cardenolides 1 reacting in alkaline solution with picric acid 2 to form stabilized Meisenheimer complexes, as shown with the resonance form 3a to 3c:[6]
See also
[edit]References
[edit]- ↑ The Etymology of Chemical Names: Tradition and Convenience vs. Rationality in Chemical Nomenclature, Walter de Gruyter & Co KG, 2019, ISBN 978-3-11-061124-3
- ↑ Entry on Baljet-Reaktion. at: Römpp Online. Georg Thieme Verlag, retrieved 2024-11-18.
- ↑ Bell, Frederick K.; Krantz, John C. (1949-02-01). "Digitalis. VIII. The Baljet Reaction, Digitoxm and Digitoxigenin". Journal of the American Pharmaceutical Association (Scientific Ed.). 38 (2): 107–109. doi:10.1002/jps.3030380214. ISSN 0095-9553. PMID 18111465.
- ↑ Siegfried Ebel, Hermann J. Roth: Lexikon der Pharmazie 1987, Georg Thieme Verlag Stuttgart, New York, ISBN 3-13-672201-9, S. 80.
- ↑ Shah, Karishma; Trivedi, Priti; Shivprakash; Pundarikakshudu, K. (2007). "Spectrophotometric determination of andrographolides in Andrographis paniculata nees and its formulation". Indian Journal of Pharmaceutical Sciences. 69 (3): 457. doi:10.4103/0250-474X.34564. ISSN 2278-8875.
- ↑ Kovar, Karl-Artur; Francas, Gernod; Seidel, Roswita (1977). "Zum Mechanismus der Reaktionen nach Raymond, Kedde und Baljet". Archiv der Pharmazie (in German). 310 (1): 40–47. doi:10.1002/ardp.19773100111. ISSN 1521-4184. PMID 843196.
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